PRISM Mid-Day Movers: Global Health and Pharmaceuticals are today’s leaders.

Silence Therapeutics (NASDAQ: SLN) jumped about 125% to roughly $19.57 by Mid-day, after agreeing to an all-cash acquisition by Merck KGaA at $20.00 per ADS. That price is a 130% premium to the October 16 close and implies an equity value of about $1.3 billion. With shares now just below the offer, upside is largely capped. The tight spread suggests investors expect the deal to close, pending approvals.

Actinium Pharmaceuticals (NYSE: ATNM) rose about 21% to roughly $1.37, from a $1.13 prior close. The rally coincides with the company’s presentation of first-in-human Phase 1 data for ATNM-400 in metastatic castration-resistant prostate cancer at EANM 2026. ATNM-400 is a non-PSMA targeted alpha therapy, a potential differentiator in a crowded radiopharmaceutical field. With a market cap near $43 million, the stock remains a volatile, early-stage microcap.

Other Notable Movers:

Cytosorbents Corp (CTSO) up 18%

Vaxart, Inc. (VXRT) up 16%

Safe Harbor Financial (SHFS) down -30%

Stock prices and percentage changes are as of 12:00 p.m. ET on October 19, 2026, and are subject to change.