PRISM Mid-Day Movers: Mental Health and Aerospace & Defense are Today’s Leaders.
VistaGen Therapeutics (NASDAQ: VTGN) surged 53.94% to $0.387 after spiking as high as $0.5476, with trading volume exploding to roughly 498 million shares—far above its 4 million-share daily average. The move extended the prior day’s momentum after VistaGen released preliminary positive data from the open-label extension of its PALISADE-4 Phase 3 study, where patients receiving intranasal fasedienol for social anxiety disorder recorded a 31.4-point average improvement on the Liebowitz Social Anxiety Scale after four months. The stock’s sharp gains reflect investor interest in the potential for the company to pursue a new FDA-aligned registrational study, although the earlier randomized portion of PALISADE-4 did not meet its primary endpoint in the overall population.
Surf Air Mobility (NYSE: SRFM) climbed 14.89% to $0.77, extending its recent momentum as shares traded above the prior session’s $0.67 close. The move followed the company’s second commercial OperatorOS agreement, this time with SkyDance Air, under which Surf Air will receive a percentage of revenue from flights managed through its Palantir-powered flight-operations software. Investors also responded to the appointment of former Palantir executive Barrett Brown as President of SurfOS to lead commercialization and customer growth.
Other Notable Movers:
Psyence Biomed Ltd (PBM) up 11%
Vince Holding Corp. (VNCE) up 9%
BioXcel Therapeutics, Inc. (BTAIQ) down -20%
Stock prices and percentage changes are as of 12:00 p.m. ET on September 23, 2026, and are subject to change.
