Bellerophon Therapeutics Doses Last Patient in Phase 3 Lung Disease Study

Bellerophon Therapeutics (Nasdaq: BLPH) has announced that the last patient has completed blinded treatment in the company’s ongoing Phase 3 REBUILD study.

Bellerophon’s Phase 3 study is evaluating INOpulse®, a proprietary pulsatile nitric oxide delivery system, for the treatment of fibrotic interstitial lung disease (fILD).

The company’s share price rose 20% following the news.

Highlights

Bellerophon expects to deliver topline results from the study in mid-2023.

The REBUILD study is a Phase 3, randomized, double-blind, placebo-controlled clinical trial evaluating the safety and efficacy of pulsed inhaled nitric oxide (iNO) in patients at risk for pulmonary hypertension associated with pulmonary fibrosis on long-term oxygen therapy.

A total of 145 fILD patients were enrolled and treated with either INOpulse at a dose of iNO45 or placebo.

If approved, INOpulse would become the first therapy to treat a broad fILD population, including patients at low-, intermediate- and high-risk pulmonary hypertension.

About Bellerophon Therapeutics

Bellerophon Therapeutics is a clinical-stage biotherapeutics company developing innovative therapies that address significant unmet medical needs in the treatment of cardiopulmonary diseases. The company is currently developing multiple product candidates under its INOpulse® program, a proprietary pulsatile nitric oxide delivery system.

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Bellerophon Therapeutics Doses Last Patient in Phase 3 Lung Disease Study

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