Quantum-Si Incorporated

Based in Branford, Connecticut, Quantum-Si Incorporated is pioneering the post-genomic era through its focus on proteomics. Since its founding in 2013, the company has developed a proprietary single-molecule detection platform designed to enable Next-Generation Protein Sequencing (NGPS). By integrating semiconductor technology with advanced biochemistry, the firm allows researchers to sequence proteins with amino acid level resolution on a simple benchtop device.

At the center of its product line are the Platinum and Platinum Pro NGPS instruments. These devices utilize a specialized semiconductor chip to capture the kinetic signatures of individual peptides in real time. In addition to the hardware, the company provides comprehensive library preparation kits that allow customers to digest and functionalize their protein samples for sequencing. Along with these preparation tools, the company sells sequencing kits containing the necessary reagents and consumables to perform high-resolution analysis.

In order to simplify the complex data generated by these runs, the firm offers the Platinum Analysis Software. This cloud-based solution automates the entire analysis workflow and provides intuitive visualizations of the sequencing results. Because of this integrated software approach, laboratories can access deep insights into protein variants and post-translational modifications without the need for extensive bioinformatics expertise. In a similar way to how genomic sequencing transformed medicine, Quantum-Si aims to democratize protein sequencing to accelerate drug discovery and scientific research.