PRISM Mid-Day Movers: Crypto Mining and Emerging Pharmaceuticals are Today’s Leaders.

Shares of GameSquare Holdings, Inc. (Nasdaq: GAME) are ripping higher, up about 56–60% in early trading as the esports and creator‑economy company spikes from roughly $0.25 to about $0.40 on heavy volume. The move follows Q4 2025 results showing revenue up 142% year over year to $18.5 million, a swing to positive adjusted EBITDA of $1.7 million, stronger 45.9% gross margins, and 2026 guidance calling for $85–$90 million in sales plus over $5 million in adjusted EBITDA, positioning GameSquare—and its FaZe, Stream Hatchet, and TubeBuddy assets—as a high‑growth but still speculative small‑cap trying to regain Nasdaq bid‑price compliance.

 

Shares of Galmed Pharmaceuticals Ltd. (Nasdaq: GLMD) are jumping, up about 42%, as traders speculate around the company’s ongoing Nasdaq‑compliance efforts and broad reverse‑split authorization. With shares still under a dollar, a tiny market cap, a disclosed going‑concern risk, and a strategy that now mixes legacy NASH/oncology work on Aramchol with a planned digital‑asset treasury initiative, GLMD remains a highly speculative micro‑cap where small bursts of buying can drive outsized percentage moves.

 

Other Notable Movers:

Eos Energy (EOSE) up 23%

Plus Therapeutics (PSTV) up 18%

IO Biotech (IOBT) down -64%

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